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(CNN) -- Secretary of State Hillary Clinton was discharged from a New York hospital on Wednesday, three days after she was admitted for treatment of a blood clot in a vein between her skull and brain, the State Department announced.

"Her medical team advised her that she is making good progress on all fronts, and they are confident she will make a full recovery," Clinton spokesman Philippe Reines said in a statement announcing her release.

Clinton walked out of New York Presbyterian Hospital accompanied by her husband, former President Bill Clinton, and daughter, Chelsea, for a brief period Wednesday afternoon. She had been admitted Sunday, after doctors found the clot during a medical test related to a concussion she suffered in December.

The secretary is being treated with blood thinners to dissolve the clot, which has not resulted in a stroke or any neurological damage. Doctors expect her to make a full recovery.

Hillary Clinton's blood clot explained

Secretary of State Hillary Clinton, pictured in October, has become one of the most powerful people in Washington. Here's a look at her life and career through the years:

Hillary Rodham, center, a lawyer for the Rodino Committee, and John Doar, left, chief counsel for the committee, bring impeachment charges against President Richard Nixon in the Judiciary Committee hearing room at the U.S. Capitol in 1974.

Arkansas Gov. Bill Clinton helps first lady Rosalynn Carter on a campaign swing through Arkansas in June 1979. Also seen is Hillary Clinton (center background).

Bill Clinton embraces his wife shortly after a stage light fell and knocked her down on January 26, 1992. They talk to Don Hewitt, producer of the CBS newsmagazine "60 Minutes."

With Hillary, Democratic presidential candidate Bill Clinton waves to the crowd during his victory party after winning the Illinois primary on March 17, 1992.

Al Gore, from left, his wife, Tipper, Bill Clinton and Hillary Clinton wave to supporters at the Chautauqua Institution in Chautauqua, New York, on August 23, 1992, after they gave speeches on family values.

Clinton gestures at a campaign rally November 3, 1992, in Denver. After taking office, President Bill Clinton chose his wife to head a special commission on health care reform, the most significant public policy initiative of his first year in office.

Bill and Hillary Clinton have a laugh together on Capitol Hill in 1993.

Clinton pours herself a cup of tea during her testimony to the Senate Education and Labor Committee on health care reform in 1993.

Clinton speaks at George Washington University on September 10, 1993, in Washington, during her husband's first term.

Clinton, left, waves to the media on January 26, 1996, as she arrives at federal court in Washington for an appearance before a grand jury. The first lady was subpoenaed to testify as a witness in the investigation of the Whitewater land deal in Arkansas.

Hillary Clinton looks on as President Bill Clinton addresses the Monica Lewinsky scandal in the Roosevelt Room at the White House on January 26, 1998.

Hillary and Bill Clinton arrive at Foundry United Methodist Church on August 16, 1998, in Washington. He became the first sitting president to testify before a grand jury when he testified via satellite about the Monica Lewinsky matter.

Clinton shakes hands during a St. Patrick's Day parade in the Sunnyside neighborhood of Queens, New York, on March 5, 2000.

Clinton waves to the crowd as she arrives on the stage at the Democratic National Convention on August 14, 2000, at the Staples Center in Los Angeles.

Clinton campaigns for a Senate seat at Grand Central Station on October 25, 2000, in New York.

First lady Hillary Clinton is sworn in as a senator in a re-enactment ceremony with U,S. President Bill Clinton, from left, nephew Tyler, daughter Chelsea, brother Hugh Rodham, mother Dorothy Rodham and Vice President Al Gore in the Old Senate Chamber on Capitol Hill on January 3, 2001, in Washington.

Andrew Cuomo, from left, Eliot Spitzer and Clinton celebrate with the crowd of Democratic supporters after their wins in their various races on November 7, 2006, in New York City.

Clinton speaks during a post-primary rally on January 8, 2007, at Southern New Hampshire University in Manchester, New Hampshire.

Hillary and Bill Clinton pay a visit to the 92nd Annual Hopkinton State Fair on September 2, 2007, in Contoocook, New Hampshire.

Clinton speaks at a fall kick-off campaign rally on September 2, 2007, in Portsmouth, New Hampshire.

Clinton addresses a question during a Democratic Presidential Candidates Debate at Dartmouth College in Hanover, New Hampshire, on September 26, 2007.

Felipe Bravo, left, and Christian Caraballo are covered with Hillary Clinton stickers in downtown Manchester, New Hampshire, on January 8, 2008.

Clinton campaigns with her daughter, Chelsea, on January 1, 2008, in Council Bluffs, Iowa, two days ahead of the January 3 state caucus.

Sen. Clinton waves as she speaks to supporters at the National Building Museum on June 7, 2008, in Washington. Clinton thanked her supporters and urged them to back Sen. Barack Obama to be the next president of the United States.

Barack Obama and Clinton talk on the plane on their way to a Unity Rally in Unity, New Hampshire, on June 27, 2008.

U.S. Democratic presidential candidate Barack Obama watches Sen. Hillary Clinton address the Democrate National Convention at a Democratic supporters' group in Billings, Montana, on August 26, 2008. The two endured a long, heated contest for the 2008 nomination.

Sen. Charles Schumer, left, looks toward Secretary of State designate Clinton as committee chairman Sen. John Kerry, center, looks on during nomination hearings on January 13, 2009, on Capitol Hill.

Clinton testifies during her confirmation hearing for secretary of state before the Senate Foreign Relations Committee on Capitol Hill on January 13, 2009, in Washington.

Clinton dances with a local choir as while visiting the Victoria Mxenge Housing Project in Philippi on the outskirts of Cape Town, Souith Africa, on August 8, 2009.

Clinton looks through binoculars toward North Korea during a visit to observation post Ouellette at the Demilitarized Zone seperating the two Koreas in Panmunjon on July 21, 2010.

Clinton walks up the steps to her aircraft at sunset as she leaves an ASEAN meeting July 23, 2010, in Hanoi, Vietnam.

From left: Marc Mezvinsky, Hillary Clinton, Chelsea Clinton and Bill Clinton pose during the wedding of the young couple at the Astor Courts Estate on July 31, 2010, in Rhinebeck, New York.

U.S. President Barack Obama and Clinton hold a moment of silence before a NATO meeting on November 19, 2010, in Lisbon, Portugal.

Clinton listens as Turkish Foreign Minister Ahmet Davutoglu (not in picture) makes a brief statement before a bilateral meeting at the State Department in Washington on November 29, 2010.

Clinton shakes hands with a child during an unannounced walk through Tahrir Square in Cairo, Egypt, on March 16, 2011.

President Barack Obama, Vice President Joe Biden, Clinton and members of the national security team receive an update on the mission against Osama bin Laden in the Situation Room of the White House on May 1, 2011.

Clinton checks her PDA upon departure in a military C-17 plane from Malta bound for Tripoli, Libya, on October 18, 2011.

Clinton speaks as Hamid Karzai, president of Afghanistan, listens during a news conference at the presidential palace in Kabul on July 7.

Clinton arrives at Ben Gurion International Airport on July 15, in Lod, outside Tel Aviv, Israel.

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

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Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

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Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

Hillary Clinton through the years

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Photos: Clinton through the years

Earlier, State Department spokeswoman Victoria Nuland told reporters that Clinton was in communication with aides and there was nothing new on her condition or treatment.

Clinton "has been quite active on the phone with all of us, but she also made some calls on Saturday to a couple of foreign officials," Nuland said.

Those official calls came before the blood clot was disclosed on Sunday. The first, to the Joint Special Envoy on Syria, Lakhdar Brahimi, lasted a half hour. The second was to the Prime Minister of Qatar, who is also the foreign minister.

"She has begun to pick up her regular phone contact with some of her counterparts," Nuland added.

Clinton, 65, has not been publicly seen or heard from in more than three weeks since falling ill with severe stomach flu and a subsequent concussion that occurred when she fainted because of dehydration, officials said.

Questions also have been raised as to why there was almost a day's delay in explaining the precise location of the clot and why she was administered an MRI, which revealed the problem.

Nuland said officials have been "extremely forthcoming" about Clinton's health.

"We will continue to keep you updated as we have new information to share, as we've been doing all along," Nuland said. "I think that was eighth statement in some three weeks so please bear with us."

Asked how Clinton's illness might affect her plans to testify on Capitol Hill about the deadly September terror attack on the U.S. diplomatic mission in Benghazi, Libya. Nuland did not directly say whether Clinton would appear.

"She has said that she is open to going up to the Hill. We are working with them now on their schedule because there's also a question of when they are going to be in and we will let you know when we have something to share," Nuland said.

Clinton, a former first lady, New York senator and presidential candidate, does not plan to stay on for President Barack Obama's second term, but prefers to remain until her replacement is in place.

Some senators have said they would delay confirmation hearings for her proposed successor, Sen. John Kerry, until Clinton has testified on the Libya attack that killed Ambassador Christopher Stevens and three other Americans.